AIDS defining illnesses, their causes and treatment
Treatment recommendations after the book „The silent Revolution in Cancer-
and AIDS-Therapy“* by MD. Heinrich Kremer, (Barcelona), and works of Prof.
Alfred Hässig (Berne), Dr. Stefan Lanka (Stuttgart), Eleni Papadopulos-Eleopulos
(Royal Hospital, Perth), Etienne de Harven (France), MD Roberto Giraldo (USA)
and Kary B. Mullis (USA) available at www.virusmyth.com and the works of L.A.
Herzenberg, J.D. Peterson et S.C. De Rosa, W. Droege, J.K. Shabert, G. Ohlenschlaeger,
C. Richter, V.Hack, H. Rode, E.A. Newsholme, C. De Simone, S.J. Ferrando, C.
de Back, M. Clerici, G.M. Shearer, M.C. Dalakas, G.Tomelleri, E. Benbrik, G.A.
Cannon, B D. Cheson, R.F. Fuchgott and C.J. Ignarro and L. Chaitow available
The many and varied diseases that can define the AIDS syndrome: fungal infections
of the lung, of the mucous membranes, the brain, and the gut, and the degenerative
changes in the endothelial cells of blood vessels and lymphatic vessels (Kaposi
Sarcoma), occur because of an ongoing change in the production of gaseous nitric
oxide and oxygen radicals in immune cells and other cells.
If these changes continue, CD4 helper cells mature predominantly
to cells with the Th2 cytokine profile, which migrate to the bone marrow where
they stimulate B cells to produce antibodies against external pathogens (bacteria
and toxins) but only a few mature into Th1 cells which activate the detection
and destruction of fungus and virus infected cells and of altered cells. If
this situation persists, the release of gaseous nitric oxide (NO) gets entirely
inhibited so that the destruction of cells carrying viruses, fungi and mycobacteria
by killer cells is blocked. Then, as an effect of heightened cell decay, a higher
quantity of proteins of the cyto-skeleton and of mitochondria is released. Against
these proteins a higher rate of antibodies are formed. These antibodies and
antibodies against a big variety of antigens and against products of toxic pollution
are detected by the HIV-tests. Once an arbitrarily set level is reached, the
patient is declared "HIV positive".
An ongoing Th1-Th2 switch in the cytokine profile of CD-4 helper
cells comes about as a result of:
- Frequent contact with antigens from repeated injuries or chronic
infections, from operations and drinking of dirty water, from re-peated
contact of foreign proteins to the plasma (from coagulation proteins in
blood preparations and from semen liquid in un-protected anal intercourse)
and repeated contact with toxic sub-stances in food (e.g. aflatoxin in wet
cereals), medicaments and environmental pollution, toxic decomposition products
from modern chemicals (e.g. fungicides, insecticides, textile colours, for-maldehyde)
and heavy metals such as mercury and aluminium in car-rier substances of
vaccines and amalgam fillings. Frequent contact with antigens, toxins and
toxic decay products cause an ongoing activation of cell mediated defence
reaction with an excessive release of gaseous nitric oxide. This leads to
a slowing down of the release of TH-1 type cytokines (to protect the tissue
from destruction) and to a heightened use of thiols, and a continuous change
in the redox potential of cells and in the end to an ongoing counter-regulation
to the TH-2 type of cytokines, that activate B-cells to a higher production
of antibodies against ex-ternal antigens (bacteria and toxins).
- The uptake of nitrites from contaminated water and food and by
inhalation ("poppers"). Nitrites inhibit the synthesis of the
TH1 type of cytokines and the ripening of T-4 cells and cause thereby and
persistent TH-1-TH-2-switch which finally leads to oncogene-sis. Nitrites
are stored in cells as NO2 and later released through physical exertion
on increased exposure to calcium ions. This affects the endothelial cells
of blood vessels and lymphatic vessels with a small capillary diameter,
and leads thereby to de-generative changes in lymph nodes (Kaposi Sarcoma).
Continuous intake of chemo antibiotics (Sulphonamides,
Trimethoprim,(such as Bactrim, Septrin, Cotrimoxazole and TMPSMX) and
of nucleoside analog drugs (such as AZT, DDI, DDC, 3TC e.g.) They inhibit
the synthesis of folic acid and purine, used in cells for the formation
of the mitochondrial DNA. They also inhibit the iron and copper containing
enzymes, bind the SH-groups of glutathione and cysteine, close the mitochondrial
membrane and impair thereby the activity of mitochondria. Mitochondria,
the suppliers of energy in human cells, synthesise, with reduced oxy-gen
and energy rich electrons from nutritional components, the energy carrier
molecule (ATP), that is used for all functions in the organism. They also
reduce toxic oxygen radicals and play an important role in the immune
system. Chemo antibiotics inhibit also the synthesis of the enzyme dihydrofolatereductase
(DHFR), which is needed for the formation of tetrahydrofolate, used in
the liver for the synthesis of cysteine and glutathione molecules, and
for the synthesis of gaseous nitric oxide (NO) used by neutrophils, killer
cells and macrophages to attack and destroy cells carrying fungi, viruses
- Chemo antibiotics, nucleoside analog drugs, insecticides (e.g. Lindan
in moistures against crablouse) and nitrites (poppers) cause, by their strongly
oxidising effect, a reduced oxygen transport in cells (methaemoglobinaemia)
which exceeds the reduc-tive capacity of glutathione molecules.
- Lower numbers of glutathione molecules produced as a result of
chemo antibiotics, liver damage (from hepatitis and frequent al-cohol consumption)
or through shortage of nutritional cysteine (esp. in developing countries).
Glutathione molecules reduce oxygen and nitric oxide molecules, so that
ATP production in mito-chondria is not disturbed. A lack of glutathione
molecules makes fungi grow, that then release toxic decay products (Azethalde-hyde),
which weaken the synthesis of glutathione molecules in the liver and can
only be decomposed by glutathione molecules and glucoronic acid. A lack
of glutathione in antigen-presenting cells makes CD-4 helper cells predominantly
mature as Th2 cells rather than TH1. TH2 cells activate the formation of
antibodies against external pathogens in the bone marrow, TH1 cells induce
the detection and destruction of cells containing viruses, myco-bacteria
and fungi by killer cells using gaseous nitric oxide (NO).
- Lack of plant antioxidants which bind to toxic degradation products
(oxygen radicals) and thereby reduce inflammation and stress reactions.
The effects of the "anti-retroviral" treatment
Chemo antibiotics inhibit the synthesis of folic acid, of purine
and of the enzyme dihydrofolatereductase (DHFR). They also damage the mitochdonrial
DNA, which is inherited from the mother to the child and inhibit the formation
of the glutathione molecules in the liver, used for the reduction and transportation
of oxygen to the cells. They also inhibit the formation of gaseous nitric oxide
(NO), used for the destruction of cells containing viruses, fungi and mycobacteria.
By doing this they block continuously the entire cellular immune reactions and
cause a lasting Th1-Th2 switch in the cytokine profile of CD-4 helper cells,
which induces an ongoing functional immune deficiency. By suffocation of the
cellular respi-ration they induce chronic fungal infestation (e.g. PCP, Candida
Albicans)in mucous membranes, in the intestine (causing chronic di-arrhoea)
and on the skin. Due to the damage on mitochondrial DNA they cause lasting energy
decline and severe damage to the brain, internal organs and to muscles, causing
heart attacks and paralysis. They also inhibit the release of tetrahydrofolate,
which is used for the synthesis of uracil. Uracil deficiency results in the
inhibition of production of the growth factor Interleukin 2. By inhibition of
production of the biologically active form of folic acid they also inhibit the
transformation of the rna-base uracil into the dna-base thymine and thereby
the repair of DNA by means of reverse transcription.
Nucleoside analog drugs (e.g. Ziduvine, Retrovir, Nevirapine)
inhibit after a short time of administration the ripening of immune cells in
the mucous membrane (B-cells, T-cells, macrophages and dendrite cells). The
damage to the ripening of B-cells causes a decrease of their number and activity
and thereby the weakening of the antibacterial defence by antibodies, which
leads to persisting bacterial infections. If TH2-T-cells then circulate they
only meet a reduced number of B-cells, that they can activate. Without the contact
to B-cells most of them circulate for 24 hours through the blood circulation
system and the lymphatic tissue, unable to activate the detection and elimination
of cells that contain viruses, fungi and mycobacteria. Then a higher rate of
T-4 cells is countable in the plasma. This measurement of T-4 cells does not
give any valid information on the defence capability in the person tested.
Nucleoside analogy drugs and protease inhibitors cause disorder
to the biological synthesis of proteins and enzymatic proteins and damage the
synthesis of nucleic acids that are needed for the for-mation of new cells in
all organs. They also change the codification patterns in the cell nucleus and
in the mitochondria DNA. Thereby they damage the DNA in the cell nucleus and
in mitochondria and the repair of DNA by means of reverse transcription (transmission
of the messenger substance RNA into DNA). The rate of RNA measurable in the
plasma then increases (increase of the so called „viral load“, „resistant
HIV viruses“). For the repair of the growing number of DNA damages occurring
after HAART treatment the consumption of RNA increases, so that the rate of
the so called „HIV-virus-particles“ measured as „viral load“
by means of the PCR-test, decreases. On prolonged impairment of mitochondria,
the mitochondria dissolve their symbiosis with the host ("Warburg Phenomenon").
The cells then increasingly switch over to producing energy by anaerobic fermentation,
which results in excess lactic acid production, the growth of fungi and opportunists,
and ultimately the formation of cancerous cells and wasting, at which point
cells obtain essential nutrients directly from mycoprotein.
Nucleoside analog drugs (e.g. AZT, DDC, DDI, 3TC), that block
for a limited time the formation of DNA in bacteria and fungi, are prac-tically
not incorporated into the cell nucleus, where they should work as DNA terminators
against HIV. As has been demonstrated by various animal trials since 1990 they
cause irreversible damage to the mitochondrial DNA and thereby damage to the
brain, the bone marrow, the muscles and internal organs and also a lasting decrease
to CD-4 and CD-8 cells, that induces opportunistic infections (cy-tomegalo virus,
herpes simplex, PCP and toxoplasmosis), which can define the AIDS-syndrome.
Synthetic protease inhibitors, which are supposed to inhibit
the formation of essential "viral particles", hinder the formation
of nucleotides needed for the formation of new cells in all organs and thereby
cause malaise, diabetes, kidney stones and liver failure in patients given them.
Administrated together with nucleoside analog drugs in the HAART treatment they
cause syndromes like those occur-ring in children with inherited defects in
the mitochondrial DNA (Kees Brinkmans in The Lancet, 25th September 1999)
Means of treatment to reconstitute cell-symbiosis and flexible
- With S-acetyl-L-Glutathione (400-600 mg/daily) tablets mixed with
ginko biloba and Anthocyane) the lack of glutathione molecules in cells
can be made up. At the beginning of treatment to reconsti-tute the balance
and in acute situations up to 5 grams daily of glutathione can be administrated
intravenously or parenterally. If digestive trouble occurs SAC can be administrated
into the mouth by a spray.
- A supply of sulphur compounds in cysteine and methionine containing
protein mixtures, (Cysteine, N-acetyl-cysteine (3-8 grams daily) can stimulate
glutathione formation in the liver.
Cysteine can also be administrated intravenously until the synthesis of
glutathione in the liver works again sufficiently.
- Co-enzyme Q10 (100 mg daily) and the antioxidant Microhydrin (Ac-tive-H)
can improve electron transport in the respiratory chain of cells. Folic
acid (5 - 30 mg daily), thrills, L-carnation (6 grams daily for 14 days),
alpha lipoic acid (300-600mg daily), vitamin B 1 (150-300mg daily), B6 and
B12, and low doses of selenium (250 micrograms daily) and zinc can support
the synthesis of ATP in mitochondria and the repair of damage to mitochondrial
- The activity of killer cells and neutrophilia can be supported
by the administration of glutamine (40 grams daily) and L-Arginine (20-30
grams daily) and of Beta 1,3-d Glucan (www.altcancer.com), RM 10 (www.hmdistributor.com)
derived from medicinal mushrooms such as Shitake and Maitake, that contain
a special mix of poly-saccharides and amino acids.
- Opportunistic infections (fungi, PCP and others) can be treated
by omega-3 fatty acids in fish oil (3 tablespoons daily) and micro algae
(e.g. chlorella 3-4 grams daily) that activate, as prostaglandin modulators,
cellular immune reactions. In difficult cases gamma-globulin, selective
cyclo-oxygenese-2 inhibitors and difluoromethylornithine as a polyamine
inhibitor can be adminis-trated.
- Parasites (e.g. worm) can inactivate NO-synthesis as tissue can
be destroyed by the attack on it by means of NO-gas. Papaya leaves (as tea
or in pills) are an effective medicament against intestinal parasites. Olipraz,
sulphur containing Dithiol-Thion (two times a week 125-250 mg) and thiocyanates
in onions, broccoli and garlic activate the detoxifying enzymes. Glucoronic
acid (in the fermented beverage kombucha, made from a fungi and green tea,
herbal medicaments (milk thistle, Liv 52) can support the liver function.
FOS (fructo-oligo-saccharides), dextro-rotory lactic acid and fermented
beverages (e.g. Kane bread beverage, Vitabiosa, EM, Mankoso), work as pre-biotics
and can diminish bacterial dis-symbiosis in the intestines. N-acetyl glucosamine,
olive oil, rice bran oil can restore the gut flora.
- Essential fatty acids in linseed oil, (thistle oil, soya oil)5-6
tablespoons daily) mixed with curd, can heighten the uptake of oxygen in
- Polyphenoles (Curcuma, Green tea, Gingko bilobae PADMA 28 (2-3
times 2 tablets daily) or Artemisia annua (available from www.nusag.com)
support the balance of the redox milieu in cells and bind to toxic oxygen
decay products. (The administration of high doses of singular polyphenols
such as vitamin C, E and beta-carotene can be counterproductive. Vitamin
C for example works in the presence of transitional metals (Iron and Copper)
in a pro-oxidative way and increases a lack in thiols.)
- Polyanions (heparin and heparinoids) in sea algae (agar), guar
shark cartilage or green mussel preparations), work as natural protease
inhibitors. They protect the negatively charged matrix, that plays an important
role in the immune system, activate the body's own antiproteases and bind
to cations that attack the cell walls. Thereby they slow down chronic inflammatory
reactions oc-curring with increased cell division.
- The balance between cell-mediated and antibody-mediated immune
reactions (Th1-Th2 switch) is itself mediated by the hormonal axis between
the hypothalamus, the hypophyse and the adrenal gland. The stress hormone
cortisol, which is released in the adrenal gland, activates the antibody-mediated
defence. Its hormonal antagonist, DHEA, which is stored all over the body
activates the cellular immune reactions. With the administration of DHEA-S
ongoing stress reactions and the heightened release of helper cells with
the Th2 profile can be brought down.
- Fungal infestations (e.g. Candida Albicans) in the intestines can
be treated effectively by Caprylic acid (Mycopril Biocare UK) de-rived from
coconut in capsules resistant to gastric acids. Grape-fruit seed extract,
Bitoin (vitamin H), Aloe Vera preparations (derived from the whole plant),
Artemisia annua, tannate plant extract, castor bean extract, dextrorotary
lactic acid, bifido bacteria and lactobacillus acidophilus and garlic are
also effec-tive. The bases of such treatment is a diet poor in sugar, refined
carbohydrates and fat but rich in fibre, bases and roughage, with high value
carbohydrates (potatoes, whole grain bread and pasta), vegetables and fruit
(plant antioxidants) and cold pressed oils, algae, Soya beans and fish but
without: iron-rich red meat, smoked meat or fish, fresh egg-white, white
wheat, sugar, alcohol, fermented or malted products, canned citrus drinks,
dried fruits or nuts, pasteurised milk, buttermilk and sour cream and products
derived or containing yeast or fungi. The acid-base balance can be restored
by mixtures of bases.
- Fungal infections can be treated locally in the throat by gargling
with honey/vinegar and on the skin by sulphur containing moistures, tea-tree
oil or emulsions with acidophilus.
- Extracts of coriander and allium ursinum and chlorella algae to
bind and remove heavy metals (mercury from vaccine carrier substances and
- Targeted stress reduction techniques, e.g. autogenic training,
stretching and massages, and refraining from excessive physical exercise
and from the frequent use of performance-enhancing drugs, e.g. sugar, coffee,
alcohol, nicotine, marijuana, amphetamines, X-tasy, cocaine, heroin and
poppers, that heighten the release of stress-hormones in the adrenal gland.
- avoiding inflammatory reactions and infections by avoiding injuries
(e.g. by protection in anal intercourse, use of herbal preparations for
sphincter muscle relaxation and refraining from the use of nitrite inhalations
- limiting the intake of coagulation proteins with blood preparations
...a flexible resistance in people with AIDS defining illnesses
can be restored.
If limited administration of antibiotics is necessary, this
basic therapy has to be continued. The treatment has to be adapted to the individual
illnesses occurring. Progress achieved by these measures to bolster the immune
system can be monitored by measuring stress hormone profiles, the T4/T8 cell
ratio, macrophage activation (neopterine test) and cutaneous anergy (DTH test:
skin reaction on antigens), and the glutathione level in plasma and in CD-4
Study Group AIDS Therapy
c/o Felix A. de Fries
Eglistr. 7 CH-8004 Zürich
E-mail : firstname.lastname@example.org; Tel./FAX:
0041 1 401 34 24
*The book by MD Heinrich Kremer is not available in English.
A translation of the therapy chapter from it will be available in summer 2004